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While this statement was directed at pharmacotherapy in general, it is more likely to be a problem with the management of chronic disease, and may be at its worst, with the management of diabetes
The optimal timeframe involves balancing the enhanced response from later initiation with the need to avoid WR, considering the complex interplay between the timing of GLP1-RAs initiation and its impact on WL and WR post-surgery
Practical requirements: Hydration, ketone monitoring, sick-day rules, and clear stop rules are non-negotiable
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That being said, some patients may experience complete removal after a few months while others may take over a year
Direct-to-consumer marketing by telehealth platforms and compounding pharmacies has fueled demand for compounded GLP-1 therapies, promoted as affordable and personalized alternatives
