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Last reviewed: May 31, 2026 Last updated: May 31, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Beyond its antioxidant role, glutathione is involved in numerous critical physiological processes [2][3][4]: Phase II detoxification: Glutathione S-transferase enzymes conjugate glutathione to xenobiotics (drugs, pollutants, carcinogens), making them water-soluble for excretion

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Both vitamin B12 deficiency and folate deficiency are more common in older people, affecting around 1 in 10 people aged 75 or over and 1 in 20 people aged 65 to 74