Finally, a basalforebrain AgRP circuit has been identified, whereby AgRP elicits increased food intake through projections directly to the BST (95)
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This meal offers protein, fiber, and complex carbohydrates
Given the heterogeneity in study populations and the predominance of post hoc analyses, further prospective research is essential to clarify these mechanisms and to evaluate whether personalized, sex-specific approaches to GLP-1 RA therapy could improve obesity treatment outcomes
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