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It helps hydrate and plump the marionette lines forming around my mouth

Patients were excluded if they met any of the following criteria: (1) receiving concomitant administration of antipsychotics, orexin receptor antagonists (ie, suvorexant and lemborexant), melatonin receptor agonists (ie, ramelteon), sedative antidepressants (ie, trazodone and mianserin), or oral administration of hydroxyzine or haloperidol

Peer review Peer review information Nature Medicine thanks John Wilding and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Lower doses mean fewer side effects, lower costs (for compounded), and more room to increase if results plateau later

While there are no direct contraindications labeled for their combined use, the way each drug influences neurotransmitters and metabolic pathways requires careful monitoring by healthcare professionals like Dr

Early findings have generated interest among researchers, although its overall effectiveness and future place in weight management are still being evaluated